Okinawa Centenarian
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Okinawa Centenarian
Study

Okinawa Centenarian StudyOkinawa Centenarian StudyOkinawa Centenarian Study

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List of Publications

 The OCS and Dr. Makoto Suzuki have published hundreds of peer-reviewed scientific publications which include scientific manuscripts, conference proceedings, books, and book chapters on aging and health. Below are selected publications of major findings of the OCS.

 

1970s–1980s

  • Sanabe, E., I. Ashitomi and M. Suzuki. (1977). “Social and medical survey of centenarians.” Okinawa Journal of Public Health 9, 98–106.
     
  • Suzuki, M., Mori, H., Asato, T., Sakugawa, H., Ishii, T., & Hosoda, Y. (1985). “Medical researches upon centenarians in Okinawa (1) – case controlled study of family history as hereditary influence on longevity.” Nihon Ronen Igakkai Zasshi (Japanese Journal of Geriatrics) 22(5), 457–467.
     
  • Takata, H., Suzuki, M., Ishii, T., Sekiguchi, S., & Iri, H. (1987). “Influence of major histocompatibility complex region genes on human longevity among Okinawan-Japanese centenarians and nonagenarians.” Lancet 2(8563), 824–826.
     
  • Akisaka, M., Asato, L., Chan, Y. C., Suzuki, M., Uezato, T., & Yamamoto, S. (1996). “Energy and nutrient intakes of Okinawan centenarians.” Journal of Nutritional Science and Vitaminology 42(3), 241–248.  (listed here because it’s part of the early OCS work and often attributed to Akisaka et al. with Suzuki coauthor on related early studies).
     

1990s

  • Akisaka, M., Suzuki, M., & Inoko, H. (1997). “Molecular genetic studies on DNA polymorphism of the HLA class II genes associated with human longevity.” Tissue Antigens 50(5), 489–493.
     
  • Akisaka, M., & Suzuki, M. (1998). “Okinawa longevity study: Molecular genetic analysis of HLA genes in the very old.” Nihon Ronen Igakkai Zasshi (Japanese Journal of Geriatrics) 35(4), 294–298.
     
  • Nozaki, H., Nohara, Y., Ashitomi, I., Zukeran, R., Inafuku, T., Akisaka, M., & Suzuki, M. (1998). “Serum globulin levels and activities of daily living in centenarians.” Nihon Ronen Igakkai Zasshi 35(9), 680–685.
     

2000–2004

  • Suzuki, M. (2001). “Cultural climate and social custom for longevity region, Okinawa.” Nihon Ronen Igakkai Zasshi (Japanese Journal of Geriatrics) 38(2), 163–165.
     
  • Suzuki, M., Willcox, B. J., & Willcox, D. C. (2001). “Implications from and for food cultures for cardiovascular disease: Longevity.” Asia Pacific Journal of Clinical Nutrition 10(2), 165–171.
     
  • Willcox, D. C., Willcox, B. J., & Suzuki, M. (2002). “Evidence-based exceptional longevity: The demography of centenarians in Japan.” J Cheju Island Studies 22, 85–86. [Korean item noted in ORCLS list]
     
  • Suzuki, M., Tamaki, M., Higa, K., & Willcox, D. C. (2003). “ADL and its relation to personality in Okinawan-Japanese community dwelling centenarians.” Okinawa International University Journal of Social Welfare and Psychology 1(1), 39–49.
     
  • Bernstein, A. M., Willcox, B. J., Tamaki, H., Kunishima, N., Suzuki, M., Willcox, D. C., … Perls, T. T. (2004). “First autopsy study of an Okinawan centenarian: Absence of many age-related diseases.” The Journals of Gerontology. Series A 59(11), 1195–1199.
     
  • Suzuki, M., Willcox, B. J., & Willcox, D. C. (2004). “Successful aging: Secrets of Okinawan longevity.” Geriatrics and Gerontology International 4(4), S180–181.
     

2005–2009

  • Willcox, D. C., Willcox, B. J., Hsueh, W. C., & Suzuki, M. (2006). “Genetic determinants of exceptional human longevity: Insights from the Okinawa Centenarian Study.” Age (Dordrecht, Netherlands) 28(4), 313–332. PubMed PMID: 22253498. PubMed
     
  • Willcox, D. C., Willcox, B. J., Todoriki, H., Curb, J. D., & Suzuki, M. (2006). “Caloric restriction and human longevity: What can we learn from the Okinawans?” Biogerontology 7(3), 173–177.
     
  • Willcox, B. J., D. C. Willcox, Wang, N. C., He, Q., Rosenbaum, M., & Suzuki, M. (2008). “They really are that old: A validation study of centenarian prevalence in Okinawa.” The Journals of Gerontology. Series A 63(4), 338–349. PubMed PMID: 18426957. PubMed
     
  • Willcox, B. J., Willcox, D. C., Todoriki, H., & Suzuki, M. (2009). “The Okinawan diet: Health implications of a low-calorie, nutrient-dense, antioxidant-rich dietary pattern low in glycemic load.” Journal of the American College of Nutrition 28 (Suppl), 516S.
     

2010–2014

  • Rosenbaum, M. W., Willcox, B. J., Willcox, D. C., & Suzuki, M. (2010). “Okinawa: A naturally calorie-restricted population.” In Calorie restriction, aging and longevity (pp. 43–53). Springer.
     
  • Suzuki, M., Willcox, D. C., Rosenbaum, M. W., & Willcox, B. J. (2010). “Oxidative stress and longevity in Okinawa: An investigation of blood lipid peroxidation and tocopherol in Okinawan centenarians.” Current Gerontology and Geriatrics Research (2010 article). PubMed PMID: 21490698. PMC
     
  • Willcox, B., Suzuki, M., Donlon, T., He, Q., Grove, J., Masaki, K., & Willcox, D. (2013). “Optimizing Human Health Span and Life Span: Insights From Okinawa and Hawaii.” Annual Review of Gerontology & Geriatrics 33, 135–154. ResearchGate
     

2010s

  • Willcox, D. C., Willcox, B. J., Yasura, S., Ashitomi, I., & Suzuki, M. (2012). “Gender gap in healthspan and life expectancy in Okinawa: health behaviours.” Asian Journal of Gerontology & Geriatrics 7, 49–58.
     
  • Willcox, B. J., Willcox, D. C., & Suzuki, M. (2017). “Demographic, phenotypic, and genetic characteristics of centenarians in Okinawa and Japan: Part 1 – Centenarians in Okinawa.” Mechanisms of Ageing and Development 165(Pt B), 75–79. PubMed PMID: 27845177. PubMed+1
     
  • Davy, P. M. C., Willcox, D. C., Shimabukuro, M., Donlon, T. A., Torigoe, T., Suzuki, M., … Willcox, B. J. (2018). “Minimal shortening of leukocyte telomere length across age groups in a cross-sectional study for carriers of a longevity-associated FOXO3 allele.” The Journals of Gerontology. Series A 73(11), 1448–1452. PubMed PMID: 29688278. orcls.org+1
     

Encyclopedia / review entries

  • Suzuki, M., Willcox, D. C., & Willcox, B. J. (2016). “Okinawa Centenarian Study: Investigating healthy aging among the world’s longest-lived people.” In Encyclopedia of Geropsychology. Singapore: Springer. doi:10.1007/978-981-287-080-3_74-1.

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